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Integration of Molecular Interactome and Targeted Interaction Analysis to Identify a COPD Disease Network Module

21 Sept 2018

Abstract excerpt

Abstract The polygenic nature of complex diseases offers potential opportunities to utilize network-based approaches that leverage the comprehensive set of protein-protein interactions (the human interactome) to identify new genes of interest and relevant biological pathways. However, the incompleteness of the current human interactome prevents it from reaching its full potential to extract network-based...

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PMID: 30262855
DOI: 10.1038/s41598-018-32173-z

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