Article

The mRNA cap 2’O methyltransferase CMTR1 regulates the expression of certain interferon-stimulated genes

2020-03-06

Abstract excerpt

Type I interferons (IFN) initiate an antiviral state through a signal transduction cascade that leads to the induction of hundreds of IFN-stimulated genes (ISGs) to restrict viral infection. Recently, RNA modifications on both host and viral RNAs have been described as regulators of infection. However, the impact of host mRNA cap modifications on the IFN response and how this regulates viral infection is unknown....

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Literature Corpus work: 0ab7a1a9-d554-5208-9a40-f48bf90aaa52
DOI: 10.1101/2020.03.05.980045

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