Article

Family history and APOE4 risk for Alzheimer’s Disease impact the neural correlates of episodic memory by early midlife

2017-01-24

Abstract excerpt

Episodic memory impairment is a consistent, pronounced deficit in pre-clinical stages of late-onset Alzheimer’s disease (AD). Individuals with risk factors for AD exhibit altered brain function several decades prior to the onset of AD-related symptoms. In the current event-related fMRI study of spatial context memory we tested the hypothesis that middle-aged adults (MA; 40-58yrs) with a family history of late onse...

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Literature Corpus work: 0a6b073a-3a12-50d1-bf0b-53c30df0c425
DOI: 10.1101/102699

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