Article
Memory performance and fMRI signal in presymptomatic familial Alzheimer's disease.
Human brain mapping - 1 Dec 2013
Braskie Meredith N, Medina Luis D, Rodriguez-Agudelo Yaneth, Geschwind Daniel H, Macias-Islas Miguel Angel, Thompson Paul M, Cummings Jeffrey L, Bookheimer Susan Y, Ringman John M
Abstract excerpt
Rare autosomal dominant mutations result in familial Alzheimer's disease (FAD) with a relatively consistent age of onset within families. This provides an estimate of years until disease onset (relative age) in mutation carriers. Increased AD risk has been associated with differences in functional magnetic resonance imaging (fMRI) activity during memory tasks, but most of these studies have focused on possession...
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