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Article

The influence of parental history of Alzheimer's disease and apolipoprotein E epsilon4 on the BOLD signal during recognition memory.

Brain : a journal of neurology - 1 Feb 2009

Xu Guofan, McLaren Donald G, Ries Michele L, Fitzgerald Michele E, Bendlin Barbara B, Rowley Howard A, Sager Mark A, Atwood Craig, Asthana Sanjay, Johnson Sterling C

Abstract excerpt

First-degree family history (FH) of sporadic Alzheimer's disease and the apolipoprotein E epsilon4 allele (APOE4) are risk factors for Alzheimer's disease that may affect brain function prior to onset of clinical symptoms. In this functional MRI (fMRI) study, we used an episodic recognition task that required discrimination of previously viewed (PV) and novel (NV) faces to examine differences in blood oxygen...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18829694
DOI: 10.1093/brain/awn254
PMCID: PMC2724919

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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