Article

SOX9 elongates cell cycle phases and biases fate decisions in human intestinal stem cells

2022-11-04

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background and Aims</h4> The transcription factor SOX9 is expressed in many stem/progenitor cell populations and has biphasic correlations with proliferation rates across different biological systems. In murine intestinal crypts, distinct Sox9 levels mark three phenotypically different cell types, with lowest levels marking rapidly-dividing transit amplifying (TA) cells, intermediate levels...

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Literature Corpus work: 09f17933-04dc-5626-853d-c77b92cf3a68
DOI: 10.1101/2022.11.03.514885

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