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Article

Distinct levels of <i>Sox9</i> expression mark colon epithelial stem cells that form colonoids in culture

13 Oct 2011

Abstract excerpt

Sox9 is an high-mobility group box transcription factor that is expressed in the stem cell zone of the small intestine and colon. We have previously used a Sox9EGFP mouse model to demonstrate that discrete levels of Sox9 expression mark small intestine epithelial stem cells that form crypt/villus-like structures in a three-dimensional culture system (Formeister EJ, Sionas AL, Lorance DK, Barkley CL, Lee GH,...

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PMID: 21995959
DOI: 10.1152/ajpgi.00277.2011

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