Article

A Development-Inspired Niche for Homeostatic Human Mini-Intestines

2022-06-12

Abstract excerpt

<h4>Summary</h4> Epithelial organoids derived from intestinal tissue, also referred to as mini-intestines or mini-guts, recapitulate many aspects of the organ in vitro and can be used for biological discovery, personalized medicine, and drug development. Murine intestinal organoids represent a homeostatic system that balances stem cell maintenance within a crypt-like compartment and differentiation within a vill...

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Literature Corpus work: 80ccd35e-cb0b-541e-b6ab-75f5fe20af0a
DOI: 10.1101/2022.06.12.495827

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