Article

<i>In vitro</i> and <i>in vivo</i> development of the human intestinal niche at single cell resolution

2020-02-01

Abstract excerpt

<h4>SUMMARY</h4> The human intestinal stem cell (ISC) niche supports ISC self-renewal and epithelial function, yet little is known about the development of the human ISC niche. We used single-cell mRNA sequencing (scRNA-seq) to interrogate the human intestine across 7-21 weeks of gestation. Using these data coupled with marker validation in situ , molecular identities and spatial locations were assigned to sever...

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Literature Corpus work: 3a378ff8-9bf1-5ef3-9546-5dbc4be346b2
DOI: 10.1101/2020.01.31.928788

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