Article
Genomic landscape of hepatocellular carcinoma in Egyptian patients by whole exome sequencing.
BMC medical genomics - 9 Aug 2024
Kassem Perihan Hamdy, Montasser Iman Fawzy, Mahmoud Ramy Mohamed, Ghorab Rasha Ahmed, AbdelHakam Dina A, Fathi Marium El Sayed Ahmad, Wahed Marwa A Abdel, Mohey Khaled, Ibrahim Mariam, Hadidi Mohamed El, Masssoud Yasmine M, Salah Manar, Abugable Arwa, Bahaa Mohamad, Khamisy Sherif El, Meteini Mahmoud El
Abstract excerpt
BACKGROUND: Hepatocellular carcinoma (HCC) is the most common primary liver cancer. Chronic hepatitis and liver cirrhosis lead to accumulation of genetic alterations driving HCC pathogenesis. This study is designed to explore genomic landscape of HCC in Egyptian patients by whole exome sequencing. METHODS: Whole exome sequencing using Ion Torrent was done on 13 HCC patients, who underwent surgical intervention (7...
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