Article
Genome-wide association study identifies high-impact susceptibility loci for HCC in North America.
Hepatology (Baltimore, Md.) - 1 Jul 2024
Hassan Manal M, Li Donghui, Han Younghun, Byun Jinyoung, Hatia Rikita I, Long Erping, Choi Jiyeon, Kelley Robin Kate, Cleary Sean P, Lok Anna S, Bracci Paige, Permuth Jennifer B, Bucur Roxana, Yuan Jian-Min, Singal Amit G, Jalal Prasun K, Ghobrial R Mark, Santella Regina M, Kono Yuko, Shah Dimpy P, Nguyen Mindie H, Liu Geoffrey, Parikh Neehar D, Kim Richard, Wu Hui-Chen, El-Serag Hashem, Chang Ping, Li Yanan, Chun Yun Shin, Lee Sunyoung S, Gu Jian, Hawk Ernest, Sun Ryan, Huff Chad, Rashid Asif, Amin Hesham M, Beretta Laura, Wolff Robert A, Antwi Samuel O, Patt Yehuda, Hwang Lu-Yu, Klein Alison P, Zhang Karen, Schmidt Mikayla A, White Donna L, Goss John A, Khaderi Saira A, Marrero Jorge A, Cigarroa Francisco G, Shah Pankil K, Kaseb Ahmed O, Roberts Lewis R, Amos Christopher I
Abstract excerpt
BACKGROUND AND AIMS: Despite the substantial impact of environmental factors, individuals with a family history of liver cancer have an increased risk for HCC. However, genetic factors have not been studied systematically by genome-wide approaches in large numbers of individuals from European descent populations (EDP). APPROACH AND RESULTS: We conducted a 2-stage genome-wide association study (GWAS) on HCC not...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.