Article

Meta-Analysis of Rare Cancers Leveraging Clinically Ascertained Cohorts Reveals Novel Germline Susceptibility Loci

2026-04-22

Abstract excerpt

Genome-wide association studies (GWAS) have advanced the understanding of germline susceptibility in common cancers, yet rare malignancies remain underexplored due to limited sample sizes. To address this gap, we conducted large-scale GWAS across 20 rare cancer types and meta-analyzed results from three cohorts: two clinically sequenced cancer center cohorts and an independent population biobank, comprising over 4...

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Literature Corpus work: fb24a54a-163e-5164-9a25-0b4ef1853a6d
DOI: 10.64898/2026.04.16.26350975

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