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Article

Tracing the expression of circular RNAs in human pre-implantation embryos

17 Jun 2016

Abstract excerpt

BACKGROUND: PolyA- RNAs have not been widely analyzed in human pre-implantation embryos due to the scarcity of materials. In particular, circular RNA (circRNA), a novel type of polyA- RNA, has not been characterized during human pre-implantation development. RESULTS: We systematically analyze polyA+ messenger RNAs (mRNAs) and polyA- RNAs in individual human oocytes and pre-implantation embryos using SUPeR-seq. We...

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PMID: 27315811
DOI: 10.1186/s13059-016-0991-3

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