Article

eIF4E1b is a non-canonical eIF4E required for maternal mRNA dormancy

2023-06-10

Abstract excerpt

Maternal mRNAs are essential for protein synthesis during oogenesis and early embryogenesis. To adapt translation to specific needs during development, maternal mRNAs are translationally repressed by shortening the polyA tails. While mRNA deadenylation is associated with decapping and degradation in somatic cells, maternal mRNAs with short polyA tails are stable. Here we report an essential role for the germline-s...

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Literature Corpus work: 822c63ad-df60-5172-8364-f46a73b9aa6b
DOI: 10.1101/2023.06.10.544440

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