Article

Maternal mRNA deadenylation is defective in <i>in vitro</i> matured mouse and human oocytes

2021-08-30

Abstract excerpt

Oocyte in vitro maturation is a technique of assisted reproductive technology that was first introduced in patients with polycystic ovarian syndrome and is now used in most fertility clinics. Thousands of genes show abnormally high expression in in vitro maturated metaphase II ( in vitro MII) oocytes compared with in vivo maturated metaphase II ( in vivo MII) oocytes in bovines, mice, and humans 1-3 . Howeve...

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Literature Corpus work: 266a59de-2cf5-5779-8d26-c2ced686a45d
DOI: 10.1101/2021.08.29.458073

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