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Article

Identification and characterization of human embryonic poly(A) binding protein (EPAB)

20 Aug 2008

Abstract excerpt

Transcriptional silencing that begins with oocyte maturation persists during the initial mitotic divisions of the embryo. Gene expression during this period largely depends on the translational activation of maternal mRNAs by cytoplasmic polyadenylation and requires an embryonic poly(A) binding protein (EPAB). EPAB has been identified in Xenopus and mouse, where it is expressed exclusively in oocytes and early...

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PMID: 18716053
DOI: 10.1093/molehr/gan047

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Identification and characterization of human embryonic poly(A) binding protein (EPAB)PMID 18716053Read ↗

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Alternative splicing of the mouse embryonic poly(A) binding protein (Epab) mRNA is regulated by an exonic splicing enhancer: a model for post-transcriptional control of gene expression in the oocyte.Semantic proximity Read ↗

Poly(A) tail length is a major regulator of maternal gene expression during the mammalian oocyte-to-embryo transitionSemantic proximity Read ↗

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The poly(A)-binding protein nuclear 1 suppresses alternative cleavage and polyadenylation sites.Semantic proximity Read ↗

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