Article

Control of poly(A)-tail length and translation in vertebrate oocytes and early embryos

2023-10-19

Abstract excerpt

<h4>SUMMARY</h4> During oocyte maturation and early embryogenesis, changes in mRNA poly(A)-tail lengths strongly influence translation, but how these tail-length changes are orchestrated has been unclear. Here, we performed tail-length and translational profiling of mRNA reporter libraries (each with millions of 3ʹ-UTR sequence variants) in frog oocytes and embryos, and fish embryos. We found that the UUUUA eleme...

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Literature Corpus work: ce334407-9c72-5d42-a2b9-412022426b51
DOI: 10.1101/2023.10.18.562922

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