Article

RNA methylation controls stress granule formation and function during erythropoiesis

2024-11-08

Abstract excerpt

Stress granules (SGs) are crucial in RNA regulation, affecting cell fate and function. SGs contain RNAs, some of which can be methylated. We studied m 6 A RNA modifications during the human CD34 + HSPCs (hCD34 + ) differentiating into erythroid cells and found that mRNAs encoding many erythroid-specific proteins had decreased methylation during differentiation. Increased levels ALKBH5 demethylase during erythro...

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Literature Corpus work: 085e20f4-fd9a-5d5f-a9f7-853dc9a1a91a
DOI: 10.1101/2024.11.07.622459

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