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Article

Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation.

Blood - 23 Jan 2014

Alvarez-Dominguez Juan R, Hu Wenqian, Yuan Bingbing, Shi Jiahai, Park Staphany S, Gromatzky Austin A, van Oudenaarden Alexander, Lodish Harvey F

Abstract excerpt

Erythropoiesis is regulated at multiple levels to ensure the proper generation of mature red cells under multiple physiological conditions. To probe the contribution of long noncoding RNAs (lncRNAs) to this process, we examined >1 billion RNA-seq reads of polyadenylated and nonpolyadenylated RNA from differentiating mouse fetal liver red blood cells and identified 655 lncRNA genes including not only intergenic,...

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Identifiers

PMID: 24200680
DOI: 10.1182/blood-2013-10-530683
PMCID: PMC3901070

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GATA1
KLF1
TAL1

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