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Article

Comprehensive Proteomic Analysis of Human Erythropoiesis

21 Jul 2016

Abstract excerpt

Mass spectrometry-based proteomics now enables the absolute quantification of thousands of proteins in individual cell types. We used this technology to analyze the dynamic proteome changes occurring during human erythropoiesis. We quantified the absolute expression of 6,130 proteins during erythroid differentiation from late burst-forming units-erythroid (BFU-Es) to orthochromatic erythroblasts. A modest...

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PMID: 27452463
DOI: 10.1016/j.celrep.2016.06.085

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