Article

N <sup>6</sup> -methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis

2018-10-31

Abstract excerpt

Many of the regulatory features governing erythrocyte specification, maturation, and associated disorders remain enigmatic. To identify new regulators of erythropoiesis, we performed a functional genomic screen for genes affecting expression of the erythroid marker CD235a/GYPA. Among validating hits were genes coding for the N 6 -methyladenosine (m 6 A) mRNA methyltransferase (MTase) complex, including, METTL14...

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Literature Corpus work: 3c2f06e1-a004-5b2c-99ad-e680527b2a05
DOI: 10.1101/457648

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