Article

Embedding single-cell experimental conditions to reveal manifold structure of cancer drug perturbation effects

2018-10-29

Abstract excerpt

Previously, the effect of a drug on a cell population was measured based on simple metrics such as cell viability. However, as single-cell technologies are becoming more advanced, drug screen experiments can now be conducted with more complex readouts such as gene expression profiles of individual cells. The increasing complexity of measurements from these multi-sample experiments calls for more sophisticated anal...

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Literature Corpus work: 085db7fb-0273-5b26-9804-ee0dfca65fe6
DOI: 10.1101/455436

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