Article

DELPHAI, AI Agent for Predicting Drug Response and Resistance

2025-09-17

Abstract excerpt

Patient-derived organoids preserve critical tumor features and drug sensitivity patterns that mirror patient clinical responses, enabling single-cell RNA sequencing analysis of drug responses. Analyzing these perturbation data presents significant computational challenges in predicting cellular responses while maintaining biological interpretability. We developed DELPHAI (Deep ExplainabLe Predictive Human-organoid...

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Literature Corpus work: 145eb78e-5372-5366-904c-df1b0f6f0379
DOI: 10.1101/2025.09.12.675826

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