Article

An integrated multi-omics investigation of W-NK1, a cytokine-primed non-engineered natural killer cell therapy product

2024-07-10

Abstract excerpt

<h4>Background</h4> Natural killer (NK) cells originate from bone marrow precursors and mediate effective anti-tumor responses. Clinical trials of cytokine-primed memory-like (ML) NK cells in acute myeloid leukemia (AML) have demonstrated activity without major toxicity, including graft-versus-host disease or cytokine release syndrome. However, broad application of non-expanded, non-engineered ML NK cells has been...

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Literature Corpus work: 0794ddff-56ce-59c2-96e8-2b4b02d4878e
DOI: 10.1101/2024.07.08.24310018

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