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Cytokine-induced Expandable Memory NK Cells with Significant Metabolic, Epigenetic Remodeling, and Persistence Properties

2025-11-28

Abstract excerpt

<title>Abstract</title> <p> Recent investigations have indicated that NK cells induced overnight with IL-12/15/18 cytokines possess memory-like characteristics (refers as CIML NK, cytokine induced memory-like NK cells), demonstrating enhanced effector function and prolonged persistence. Preclinical studies and very early clinical trials revealed the promising clinical activity of CIML NK cells in the treatment o...

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Literature Corpus work
366897e7-1fc8-5399-9b33-8c8e151a46e9
DOI
10.21203/rs.3.rs-8091256/v1
Open publication

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Cytokine-induced Expandable Memory NK Cells with Significant Metabolic, Epigenetic Remodeling, and Persistence PropertiesDOI 10.21203/rs.3.rs-8091256/v1
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