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Single-cell neural network classifiers reveal that PM21 NK cell expansion is dependent on B cell signaling

2025-09-25

Abstract excerpt

<h4>ABSTRACT</h4> In the field drug development ML/AI methods are being applied to improve drug production speed, costs, and reliability. In allogenic NK cell therapy production, one of the biggest challenges is the inherent variability in the donors that provide the starting material for NK cell expansion. In this study we performed PM21-mediated NK cell expansion on 26 donors, and in parallel performed single-c...

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Literature Corpus work
96732797-dcea-55f3-876e-15bf8d9b870e
DOI
10.1101/2025.09.23.676816
Open publication

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Single-cell neural network classifiers reveal that PM21 NK cell expansion is dependent on B cell signalingDOI 10.1101/2025.09.23.676816
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