Article

Characterization of The Heterogeneity of Bone Marrow in NK-AML (M4/M5) Based on Single Cell RNA Sequencing

2022-10-26

Abstract excerpt

Normal karyotype acute myeloid leukemia (NK-AML) is a heterogeneous hematological malignancy that composes a minor of self-renewing leukemia stem cells (LSC), complicating efforts to achieve long-term survival. We performed single-cell RNA sequencing to profile 39288 cells from 6 bone marrow aspirates, including 5 NK-AML(M4/M5) patients and 1 healthy donor. The single cell transcriptome atlas and the gene expressi...

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Literature Corpus work: 25215081-3b39-5daa-9715-b7b7915090bb
DOI: 10.21203/rs.3.rs-2186002/v1

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