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Single-cell profiling of human bone marrow reveals multiple myeloma progression is accompanied by an increase in CD56 <sup>bright</sup> bone marrow resident NK cells

2025-03-02

Abstract excerpt

Natural killer (NK) cells play a key role in the innate immune response against tumour progression. While the immune microenvironment in multiple myeloma (MM) becomes increasingly dysfunctional during disease evolution, little is known about changes in the NK cell compartment. Using primary samples from clinical trial patients, we performed detailed phenotypic analyses of bone marrow mononuclear cells from MGUS, S...

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Literature Corpus work
ec68bbcb-a903-5a7e-8e80-c72bafc81a39
DOI
10.1101/2025.02.26.640356
Open publication

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Single-cell profiling of human bone marrow reveals multiple myeloma progression is accompanied by an increase in CD56 <sup>bright</sup> bone marrow resident NK cellsDOI 10.1101/2025.02.26.640356
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