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A Pan-Pneumovirus vaccine based on immunodominant epitopes of the fusion protein

2022-02-24

Abstract excerpt

Respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) are two leading causes of severe respiratory infections in children, the elderly, and immunocompromised patients. The fusion (F) protein is the major target of neutralizing antibodies. Recent developments in stabilizing the pre-fusion conformation of the F proteins, and identifying immunodominant epitopes that elicit potent neutralizing antibodies...

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Literature Corpus work
07893d83-2697-58b5-8517-00c920704856
DOI
10.1101/2022.02.24.481832
Open publication

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A Pan-Pneumovirus vaccine based on immunodominant epitopes of the fusion proteinDOI 10.1101/2022.02.24.481832
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