Article

New mucosal bivalent live-attenuated vaccine is protective against Human Metapneumovirus and Respiratory Syncytial Virus

2023-11-02

Abstract excerpt

<title>Abstract</title> <p>Live-Attenuated Vaccines (LAVs) stimulate robust mucosal and cellular responses and have the potential to protect against Respiratory Syncytial Virus (RSV) and Human Metapneumovirus (HMPV), the main etiologic agents of viral bronchiolitis and pneumonia in children. We inserted the RSV-F gene into an HMPV-based LAV (Metavac®) we previously validated for the protection of mice against HMP...

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Literature Corpus work: 57375a5a-e0a5-5149-a723-e19c2eb82538
DOI: 10.21203/rs.3.rs-3486319/v1

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