Article

A potently neutralizing and protective human antibody targeting antigenic site V on RSV and hMPV fusion glycoprotein

2024-11-01

Abstract excerpt

<h4>ABSTRACT</h4> Human respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) are frequent drivers of morbidity and mortality in susceptible populations, most often infantile, older adults, and immunocompromised. The primary target of neutralizing antibodies is the fusion (F) glycoprotein on the surface of the RSV and hMPV virion. As a result of the structural conservation between RSV and hMPV F, thr...

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Literature Corpus work: 57f06ceb-2a26-5ac9-b718-18e74912cd72
DOI: 10.1101/2024.10.31.621295

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