Article
Identification of antibody neutralization epitopes on the fusion protein of human metapneumovirus.
The Journal of general virology - 1 Dec 2008
Ulbrandt Nancy D, Ji Hong, Patel Nita K, Barnes Arnita S, Wilson Susan, Kiener Peter A, Suzich JoAnn, McCarthy Michael P
Abstract excerpt
Human metapneumovirus (hMPV) is genetically related to respiratory syncytial virus (RSV); both cause respiratory tract illnesses ranging from a mild cough to bronchiolitis and pneumonia. The F protein-directed monoclonal antibody (mAb) palivizumab has been shown to prevent severe lower respiratory tract RSV infection in animals and humans. We have previously reported on a panel of mAbs against the hMPV F protein...
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