Article

Mild dyserythropoiesis and b-like globin gene expression imbalance due to the loss of histone chaperone ASF1B

2020-09-14

Abstract excerpt

<title>Abstract</title> <p>The expression of the human b-like globin genes follows a well-orchestrated developmental pattern, undergoing two essential switches, the first one during the first weeks of gestation (e to g), and the second one during the perinatal period (g to b). The g to b globin gene switching mechanism includes suppression of fetal (g-globin, HbF) and activation of adult (b-globin, HbA) globin ge...

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Literature Corpus work: 0735f46a-eabf-57dc-8dc2-2a9780459686
DOI: 10.21203/rs.3.rs-44936/v3

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