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Article

Delayed fetal hemoglobin switching in subjects with KLF1 gene mutation.

Blood cells, molecules & diseases - 15 Jan 2012

Satta Stefania, Perseu Lucia, Maccioni Liliana, Giagu Nicolina, Galanello Renzo

Abstract excerpt

Variations at the KLF1 gene have been associated with a series of human erythroid phenotypes including the In-(Lu) phenotype, hereditary persistence of fetal hemoglobin, congenital dyserythropoietic anemia, borderline HbA(2) and increased red blood cell protoporphyrin. Natural mutations have shown that KLF1 regulates gamma globin gene expression and its role in the switching from fetal to adult globin expression...

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Source

Identifiers

PMID: 22093801
DOI: 10.1016/j.bcmd.2011.10.003

Genes

KLF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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