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Update on fetal hemoglobin gene regulation in hemoglobinopathies

14 Dec 2010

Abstract excerpt

PURPOSE OF REVIEW: The developmental switch from fetal to adult hemoglobin has long fascinated biologists and attracted hematologists given its importance for patients with hemoglobin disorders. New discoveries have reinvigorated the field of globin gene regulation. These results hold promise for improved treatment of the major hemoglobinopathies. RECENT FINDINGS: Both genome-wide association studies and...

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PMID: 21157349
DOI: 10.1097/mop.0b013e3283420fd0

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