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Article

Loss of one Engrailed1 allele enhances induced α-synucleinopathy

2019-01-26

Abstract excerpt

<h4>Background:</h4> Parkinson’s disease (PD) is a synucleinopathy that has multiple neuropathological characteristics, with nigrostriatal dopamine system degeneration being a core feature. Current models of PD pathology typically fail to recapitulate several attributes of the pathogenic process and neuropathology. We aimed to define the effects of combining a mouse model exhibiting multiple PD-like changes with...

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Literature Corpus work
0698fe07-8a4d-5105-951b-13b8d816cbd5
DOI
10.1101/530915
Open publication

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Loss of one Engrailed1 allele enhances induced α-synucleinopathyDOI 10.1101/530915
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