Article

Direct visualization of human myosin II force generation using DNA origami-based thick filaments

2019-05-13

Abstract excerpt

Muscle contraction can be explained by the swinging lever-arm model. However, the dynamic features of how the myosin head swings the lever-arm and its initial interactions with actin are not well understood even though they are essential for the muscle force generation, contraction speed, heat production, and response to mechanical perturbations. This is because myosin heads during force generation have not been d...

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Literature Corpus work: 065e613a-45b2-5ff1-9c51-11e200bb9d2d
DOI: 10.1101/634287

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