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Article

A mutant heterodimeric myosin with one inactive head generates maximal displacement.

The Journal of cell biology - 4 Aug 2003

Kad Neil M, Rovner Arthur S, Fagnant Patricia M, Joel Peteranne B, Kennedy Guy G, Patlak Joseph B, Warshaw David M, Trybus Kathleen M

Abstract excerpt

Each of the heads of the motor protein myosin II is capable of supporting motion. A previous report showed that double-headed myosin generates twice the displacement of single-headed myosin (Tyska, M.J., D.E. Dupuis, W.H. Guilford, J.B. Patlak, G.S. Waller, K.M. Trybus, D.M. Warshaw, and S. Lowey. 1999. Proc. Natl. Acad. Sci. USA. 96:4402-4407). To determine the role of the second head, we expressed a smooth...

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PMID: 12900396
DOI: 10.1083/jcb.200304023
PMCID: PMC2172693

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Source receipt: pubmed, retrieved 7 Sept 2026.

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