Article

The endo-lysosomal system drives lumen formation in a human epiblast model

2025-08-04

Abstract excerpt

<h4>ABSTRACT</h4> The formation of a central lumen in the epiblast is a critical step that occurs during implantation in the human embryo. Lumen formation is accompanied by highly dynamic and complex cargo trafficking in the endo-lysosomal system. However, our understanding of key players and machineries that control this critical trafficking process remains incomplete in the context of epiblast development. Here...

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Literature Corpus work: 064bc8b5-0009-510b-a8c1-7284b32473bb
DOI: 10.1101/2025.08.04.668503

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