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The enpp4 ectonucleotidase regulates kidney patterning signalling networks in <i>Xenopus</i> embryos

2021-03-05

Abstract excerpt

The enpp ectonucleotidases regulate lipidic and purinergic signalling pathways by controlling the extracellular concentrations of purines and bioactive lipids. Although both pathways are key regulators of kidney physiology and linked to human renal pathologies, their roles during nephrogenesis remain poorly understood. We previously showed that the pronephros was a major site of enpp expression and now demonstrate...

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Literature Corpus work
26c5ac8a-278a-5997-8318-c98a9d33baf0
DOI
10.1101/2021.03.04.433320
Open publication

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The enpp4 ectonucleotidase regulates kidney patterning signalling networks in <i>Xenopus</i> embryosDOI 10.1101/2021.03.04.433320
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