Article

Presynaptic precursor vesicles originate from the <i>trans</i> -Golgi network, promoted by the small GTPase RAB2

2020-06-03

Abstract excerpt

<h4>Summary</h4> Reliable delivery of presynaptic material, including active zone and synaptic vesicle proteins from neuronal somata to synaptic terminals is prerequisite for faithful synaptogenesis and neurotransmission. However, molecular mechanisms controlling the somatic assembly of presynaptic precursors remain insufficiently understood. Here we show that in mutants of the small GTPase RAB2 active zone and s...

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Literature Corpus work: 7a732a1f-6b0c-5815-8c59-0a5a20c4937c
DOI: 10.1101/2020.06.02.128991

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