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Article

Apical Lumen Formation in Renal Epithelia

4 Jun 2009

Abstract excerpt

The ability to form epithelial lumina is a central architectural characteristic of virtually all organs and indispensable for their function. Ontogenetically, the kidney is one of the best-characterized organs, but concepts of the regulated formation of its hollow epithelial structures are still emerging. Epithelial cell lines provide the opportunity to study molecular mechanisms in simplified assays modeling...

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PMID: 19497970
DOI: 10.1681/asn.2008090949

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