Article

Spatially Resolved Phosphoproteomics Reveals Fibroblast Growth Factor Receptor Recycling-driven Regulation of Autophagy and Survival

2021-12-04

Abstract excerpt

<h4>Summary</h4> Receptor Tyrosine Kinase (RTK) endocytosis-dependent signalling drives cell proliferation and motility during development and adult homeostasis, but is dysregulated in diseases, including cancer. The recruitment of RTK signalling partners during endocytosis, specifically during recycling to the plasma membrane, is still unknown. Focusing on Fibroblast Growth Factor Receptor 2b (FGFR2b) recycling,...

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Literature Corpus work: 0638e117-7891-55cb-9779-bbcd59f639d1
DOI: 10.1101/2021.12.04.471203

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