Article
Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis.
Nature - 7 Jul 2005
Pelkmans Lucas, Fava Eugenio, Grabner Hannes, Hannus Michael, Habermann Bianca, Krausz Eberhard, Zerial Marino
Abstract excerpt
Endocytosis is a key cellular process, encompassing different entry routes and endocytic compartments. To what extent endocytosis is subjected to high-order regulation by the cellular signalling machinery remains unclear. Using high-throughput RNA interference and automated image analysis, we explored the function of human kinases in two principal types of endocytosis: clathrin- and caveolae/raft-mediated...
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