Article
Systems survey of endocytosis by multiparametric image analysis.
Nature - 11 Mar 2010
Collinet Claudio, Stöter Martin, Bradshaw Charles R, Samusik Nikolay, Rink Jochen C, Kenski Denise, Habermann Bianca, Buchholz Frank, Henschel Robert, Mueller Matthias S, Nagel Wolfgang E, Fava Eugenio, Kalaidzidis Yannis, Zerial Marino
Abstract excerpt
Endocytosis is a complex process fulfilling many cellular and developmental functions. Understanding how it is regulated and integrated with other cellular processes requires a comprehensive analysis of its molecular constituents and general design principles. Here, we developed a new strategy to phenotypically profile the human genome with respect to transferrin (TF) and epidermal growth factor (EGF) endocytosis...
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