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Article

Chromatin accessibility landscape of articular knee cartilage reveals aberrant enhancer regulation in osteoarthritis

2018-03-01

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Osteoarthritis (OA) is a common joint disorder with increasing impact in an aging society; however, there is no cure or effective treatments so far due to lack of sufficient understanding of its pathogenesis. While genome-wide association studies (GWAS) and DNA methylation profiling identified many non-coding loci associated to OA, the interpretation of them remains challeng...

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Literature Corpus work
06282d17-9f53-50c5-b3a2-6be99b9353bf
DOI
10.1101/274043
Open publication

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Chromatin accessibility landscape of articular knee cartilage reveals aberrant enhancer regulation in osteoarthritisDOI 10.1101/274043
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