Article

Proteomics reveals unique identities of human TGF-β-induced and thymus-derived CD4 <sup>+</sup> regulatory T cells

2021-11-02

Abstract excerpt

The CD4 + regulatory T (Treg) cell lineage, as defined by FOXP3 expression, comprises thymus-derived (t)Treg cells and peripherally induced (p)Treg cells. In human, naïve tTreg cells can be isolated from blood, while effector tTreg and pTreg cells cannot be purified reliably for lack of cell surface markers. As a model for Treg cells, studies often employ TGF-β-induced (i)Treg cells generated from CD4 + conventi...

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Literature Corpus work: 05e53755-e577-59fa-ab88-393967db119f
DOI: 10.1101/2021.10.30.466569

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