Article
CPHEN-016: Comprehensive phenotyping of human regulatory T cells.
Cytometry. Part A : the journal of the International Society for Analytical Cytology - 1 Dec 2022
Benamar Mehdi, Chen Qian, Wang Muyun, Chan Tsz Man Fion, Chatila Talal A
Abstract excerpt
Peripheral immunological tolerance is mainly maintained by regulatory T (Treg) cells, a specific CD4 T cells subset that expresses the transcription factor Foxp3. Treg cells are crucial to control autoimmunity and inflammation and to limit tissue destruction arising from inflammatory responses. Loss of functions mutations in FOXP3 in humans induces a fatal autoimmune lymphoproliferative disorder, known as Immune...
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