Article

Breast cancer extracellular vesicles transfer P2X7 signaling competence to endothelial cells and dynamically remodel vascular migration

2026-07-31

Abstract excerpt

<h4>ABSTRACT</h4> Communication between tumor cells and the vascular endothelium is a key determinant of tumor progression and angiogenesis. Purinergic signaling critically regulates endothelial migration, permeability, and vascular plasticity. Our previous findings showed that strong purinergic stimulation exerts anti-migratory and vessel-normalizing effects in tumor-derived endothelial cells, suggesting that pu...

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Literature Corpus work: 05bd1cb1-45cc-5e8e-8250-1fbc20eef491
DOI: 10.64898/2026.07.31.741755

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