Article

Extracellular vesicles induce aggressive phenotype of luminal breast cancer cells by PKM2 phosphorylation

2021-02-08

Abstract excerpt

The aerobic glycolysis is a hallmark of cancer glucose metabolism. Several studies have suggested that cancer-derived extracellular vesicles (EVs) can modulate glucose metabolism in adjacent cells and promote disease progression. Here we suggest that EVs originated from cancer cell with highly glycolytic activity can modulate glucose metabolism in the recipient cancer cells with relative low glycolytic activity, a...

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Identifiers and source

Literature Corpus work: 2130c863-956a-5f99-a576-33d334a327cb
DOI: 10.1101/2021.02.08.430192

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